In this double-blinded, sham-controlled, counterbalanced, and crossover study, we investigated the potential neuroplasticity underlying pain relief and daily function improvements following repetitive transcranial magnetic stimulation of the motor cortex (M1-rTMS) in fibromyalgia syndrome (FMS) pati …

2024年11月26日 · M1-rTMS has immediate effects on modulating cortical α-oscillations during pain anticipation and nociceptive processing, while DLPFC-rTMS exerts delayed effects on the global brain networks...

2024年12月10日 · 单侧m1区的rtms治疗. 基于半球间抑制（ihi）模型，对于脑卒中后上肢运动功能障碍，有两种标准的rtms治疗方案： 1. 低频rtms作用于健侧m1区：降低健侧m1区的兴奋性，减少对患侧半球的过度抑制。 2. 高频rtms作用于患侧m1区：提高患侧m1区的兴奋性，促进功能恢复。

2022年8月4日 · High-frequency rTMS could alleviate ischemic stroke injury through inhibiting M1 microglia polarization via regulating let-7b-5p/HMGA2/NF-κB signaling pathway in MCAO models. Microglia assume opposite phenotypes in response to ischemic brain injury, exerting neurotoxic and neuroprotective effects under different ischemic stages.

2021年12月16日 · Repetitive transcranial magnetic stimulation (rTMS) has been proposed to treat neuropathic pain but the quality of evidence remains low. We aimed to assess the efficacy and safety of neuronavigated rTMS to the primary motor cortex (M1) or dorsolateral prefrontal cortex (DLPFC) in neuropathic pain ov …

2023年2月23日 · 一项对照研究 (Azin et al.，2016)评估了对震颤复发性多发性硬化 (RRMS)患者左侧M1区（手部）应用iTBS的治疗效果。 结果显示患者的手部灵活性有明显改善。 另一项研究 (Korzhova et al.，2019)针对继发性多发性硬化症患者，结果显示，iTBS刺激的患者痉挛症状减轻且维持12周。 一项Ⅲ类对照研究（Gaede et al., 2017），以0.5Hz、90%RMT、1500脉冲的治疗方案，结果发现组间癫痫的发作频率没有统计学差异性。 该结果与另外一项Meta分析（Hsu …

2025年1月1日 · Here, we investigated whether M1-rTMS influenced cortical excitability and oscillatory dynamics within the α- and β-bands in humans by stimulating local motor (M1) and extra-motor (DLPFC, ACC, and PSI) cortices with TMS-EEG before and after M1 rTMS in a sham-controlled setting.

2022年6月10日 · In this review, we summarize the latest evidence on using M1-rTMS to treat non-motor symptoms of diverse etiologies and discuss the potential mechanistic rationale behind the management of each of these symptoms.

5 天之前 · Women aged ≥18 yr with fibromyalgia refractory to best available treatment were enrolled in Brazil, France, and Japan, and randomised to 10 Hz motor cortex (M1) rTMS, 3000 pulses day −1, or sham stimulation.This included 10 induction sessions over 2 weeks, followed by weekly maintenance (6 weeks), and fortnightly extended maintenance (8 weeks).

2024年7月1日 · High-frequency rTMS (5 Hz or above) targeting the primary motor cortex (M1) is associated with the reduction of neuropathic pain [4]. Due to small-to-medium treatment efficacy, however, efforts have been made to improve the analgesic efficacy, including exploring alternative treatment targets such as the dorsolateral prefrontal cortex (DLPFC).