Identification of Cyclin-dependent Kinase 1 Specific Phosphorylation Sites by an In Vitro Kinase Assay

SOLVED: Which of the following causes pyruvate dehydrogenase kinase to catalyze the phosphorylation and inactivation of E1 in the pyruvate dehydrogenase complex? Elevated concentrations of NADH and ATP, insulin, elevated concentrations of acetyl CoA, elevated concentrations of NAD and ADP.

SOLVED:Two protein kinases, K 1 and K 2, function sequentially in an intracellular signaling pathway. If either kinase contains a mutation that permanently inactivates its function, no response is seen in cells when an extracellular signal is received. A different mutation in K 1 makes it permanently active, so that in cells containing that mutation a response is observed even in the absence of an extracellular signal. You characterize a double-mutant cell that contains K 2 with the inactivating

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Phosphatidylinositol Biphosphate (PIP2) Signal Pathway

SOLVED: Protein tyrosine kinase activity following T-cell stimulation:Select one: Phosphorylates and thereby activates phospholipase Cγ1 b. Is an inherent property of the T-cell receptor α and β chains c. Is an inherent property of CD3d. Is decreasedIs unrelated to phosphorylation of the CD3-associated ε chains