Total Synthesis & Medicinal Chemistry - The Davies Group

SOLVED: When the reaction of tosyl chloride and an alcohol is performed with triethyl amine instead of pyridine, an unwanted byproduct is often formed in small quantities. Propose a mechanism (show arrow-pushing) that can account for the byproduct formation. Include a BRIEF rationale/explanation for your mechanism (explain the key points and why it makes sense to you). (15 pts)(Tosyl chloride)(Desired product)(Undesired byproduct)(Triethyl amine)

PPT - Organic Synthesis: Total Synthesis of Target Molecules PowerPoint Presentation - ID:992749

What is a tosylate group?... | Filo

Are triflate, tosylate and mesylate nucleophilic? | Socratic

SOLVED: Carbocations: Rank 2-methyl-2-butyl tosylate, 3-methyl-2-butyltosylate, and 3-methylbutyl tosylate by the ease with which theyionizeRank the compounds by the ease with which they ionize underacidic conditions.Rank the compounds from easiest to hardest. To rank items asequivalent, overlap them.

consider the reaction between an alcohol and tosyl chloride followed by a nucleophile write the condensed formula of the expected main organic product 1 tscl pyridine choh 2 ch chch s chchch 69553

Some Reactions of Azides

SOLVED: Which action could produce a carbonyl group?a. the replacement of the -OH of a carboxyl group with hydrogenb. the addition of a thiol to a hydroxylc. the addition of a hydroxyl to a phosphated. the replacement of the nitrogen of an amine with oxygen