Tyrosine Kinase 2 | Research | BMS Science | HCP Site

Receptor Tyrosine Kinase: Activation and...

SOLVED:Tyrosine kinase receptors are pairs of proteins that span the plasma membrane. On the extracellular side of the membrane, one or more sites are present that bind to signaling ligands such as insulin or growth factors. On the intracellular side, the ends of peptide chains on each protein phosphorylate the other member of the pair, providing active docking sites that initiate cellular responses. The signal is switched off by dissociation of the ligand. For each ligand-receptor system, the e

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