Ankylosing Spondylitis / It's Symptoms / It's Treatable or not ? Ankylosing spondylitis (AS) is a chronic inflammatory disease primarily affecting the spine and the sacroiliac joints in the pelvis. It leads to pain and stiffness in the back, and in severe cases, it can cause the vertebrae to fuse together, resulting in a rigid spine. Symptoms : Chronic pain and stiffness in the lower back and hips, especially in the morning or after periods of inactivity. Other symptoms can include fatigue, redu