The importance of pregnenolone

The “pregnenolone steal” refers to the endocrine system where the body’s production of pregnenolone is diverted towards cortisol synthesis at the expense of other hormones, such as progesterone, DHEA, and sex hormones. This is particularly relevant in the context of chronic stress and excess cortisol production. Here’s how it works: 1. **Pregnenolone Production**: Pregnenolone is a precursor hormone synthesized from cholesterol. It serves as the starting material for the production of various ot

Pregnenolone: Harmful or Harmless To AFS?