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Gonadotrophin-releasing hormone (GnRH) stimulates the production of follicle-stimulating hormone (FSH) and luteinizing hormone (LH). The concentration of these hormones over time in females regulates the menstrual cycle. GnRH expressing neurons (GEN) are scattered throughout the forebrain and hypothalamus and secrete into ducts leading to the pituitary gland, causing the secretion of FSH and LH into the bloodstream. Ca 2 concentrations oscillate in time, changing the electric membrane potential
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